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ESTIMATION OF PROTHROMBIN TIME, ACTIVATED PARTIAL THROMBOPLASTIN TIME AND PLATELETS COUNT IN DIABETES TYPE II PATIENTS IN KHARTOUM STATE
Abstract
This is an analytical case control study, conducted during the period from
July to November in Best Care Hospital. The study aimed to evaluate
prothrombin time, international normalized ratio (INR), activated partial
thromboplastin time and platelets count among patients with diabetes
type II. Thirty samples were collected from 12 males and 18 females their
age range between 30—80 and a means of 51 years, and diabetic duration
from 1—30 years. The patients were divided into diabetic controlling and
un-controlling groups in respect to level of HbA1C (less than 8%, more
than 8%) respectively.
Thirty control samples were collected from healthy non diabetic
volunteers with same age ranges. All subjects were questionnaired during
blood collection about some clinical information. Blood samples and
controls were investigated for PT, INR, APTT and Platelets count using
coagulometer and sysmex semi-automated, hematology analyzer
respectively. There was no significant difference in PT, INR, APTT and
platelets count in diabetic patients compare with control group (P-value
0.893, 0.971,0.321 and 0.703) respectively. The results obtained show that diabetic patients have normal coagulation mechanisms.
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