AN EVALUATION ON THE ACCURACY OF ULTRASOUND IN THE DETECTION OF HEPATITIS

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AN EVALUATION ON THE ACCURACY OF ULTRASOUND IN THE DETECTION OF HEPATITIS

CHAPTER ONE

INTRODUCTION

1.1 Background of the study

Hepatitis B virus (HBV) infection is the world’s most common type of liver infection that th- reatens human health globally. China is one of the countries with the highest pre- valence of HBV infection. HBV is a viral in- fection that attacks the liver and can cause both acute and chronic disease, such as liver fibrosis, cirrhosis, ascites and even liver cancer . Liver fibrosis is a pathological process that caused by various chronic liver injuries, and liver fibrosis would progress to cirrhosis with- out intervention . For the above reasons, the diagnosis and detection of liver fibrosis is par- ticularly important.

There is no significant difference between early fibrosis and normal tissue on conventional ultrasound, thus it can only detect cirrhosis when in the final stage, in which no treatment can reverse liver fibrosis . It is shown that though there is no significant morphology change in the early stage of cirrhosis, the tissue elasticity has already changed, and early detection of this change can diagnose early liver fibrosis.

1.2 Statement of the problem

Currently, the gold standard for liver fibrosis diagnosis is liver biopsy, which is seldom accepted by the majority of patients due to its potential risks and complications, and biopsy cannot be used for the dynamic monitor of fibrosis staging . Therefore, non-invasive fibrosis evaluation method is being developed in recent years. Real-time elastography (RTE) is widely applied in superficial organ detection, and its use in liver fibrosis diagnosis has been explored lately [8, 9]. Sound velocity tissue quantification (SVQ) is a new kind of ultrasound imaging technology that has been used for tis- sue elasticity evaluation by tracking sound velocity . In this study, SVQ and RTE were compared for the detection of liver fibrosis.

1.3 Objectives of the study

1. To understand the impact of the evaluation of the accuracy of ultrasound in the detection of hepatitis

2. To identify the relationship between the accuracy of ultrasound and the detection of hepatitis

1.4 Research questions

1. What is the impact of the evaluation of the accuracy of ultrasound in the detection of hepatitis?

2. What is the relationship between the accuracy of ultrasound and the detection of hepatitis?

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